Chemical Crunch
Chemical Crunch
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Anti Malarial

Offering you a complete choice of products which include amodiaquine hydrochloride, artemether, artesunate, chloroquine phosphate, chlorphenesin and lumefantrine.
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Amodiaquine Hydrochloride

Amodiaquine Hydrochloride
 
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Approx. Rs 2,000 / KilogramGet Latest Price

Product Details:
UsageLaboratory
BrandChemical Crunch
Grade StandardReagent Grade
Packaging Size25 Kg
Usage/ApplicationAnti Malarial
Manufacturing ProcessChemical Synthesis
Packaging TypeDrum
AppearanceYellow crystalline powder
FormulaC20H22ClN3O
Molar Mass355.861 g/mol

Amodiaquine Hydrochloride is the hydrochloride salt of amodiaquine, an orally active 4-aminoquinoline derivative with antimalarial and anti-inflammatory properties. Similar in structure and activity to chloroquine, amodiaquine is effective against some chloroquine-resistant strains, particularly Plasmodium falciparum, the most deadly malaria parasite. Although the mechanism of plasmodicidal action has not been fully elucidated, like other quinoline derivatives, amodiaquine likely is able to inhibit heme polymerase activity in the body. This results in accumulation of free heme, which is toxic to the parasites.

Specification:

Test Items

Specification

Test Results

Description

Yellow crystalline powder

 

Completeness of solution

2% of water solution for this product should clear

Complies

Identification

Positive

Positive

Water

7.0%-9.0%

8.2%

Residue on ignition

≤0.2%

0.05%

Chromatographic purity

≤0.5%

0.5%

Organic volatile impurities

Alcohol ≤5000ppm

337ppm

(C20H22ClN3O·2HCl)

Assay(C20H22ClN3O·2HCl)

97.0%-

99.8%

Microbial limit

Bacteria≤1000 CFU/g

10 CFU/g

Fungi≤100 CFU/g

10 CFU/g

E. coli Should not be detected

Absent

Conclusion

The quality of the above commodity complies standard of USP31 and in house standard

 

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Artemether

Artemether
 
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Approx. Rs 14,000 / KilogramGet Latest Price

Product Details:
Physical StatePowder
BrandChemical Crunch
Package TypeDrum
ApplicationAnti Malarial
ColourWhite
CAS No71963-77-4
Molecular FormulaC16H26O5
Molecular Weight298.38

According to pharmacological study, Artemether Powderhas a direct kill effect on plasmodium at erythrocytic stage, but invalid at organizational stage. Clinical research shows that Artemether Powderhas none of toxic and side effects in clinical treatment of tertian malaria, even the time of malignant protozoon turn to negative is faster than aralen, especially superior for the treatment of malignant malaria and cerebral malaria in anti-aralen-protozoon–strains area.
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Artesunate

Artesunate
 
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Approx. Rs 1,300 / KilogramGet Latest Price

Product Details:
UsageIndustrial
Usage/ApplicationAnti Malarial
Physical StatePowder
Type Of APIInnovative
ColorWhite
Pack Size25 Kg
AppearanceWhite powder
CAS No88495-63-0
Molecular FormulaC19H28O8
Molecular Weight384.42

Product Description:
  • Artesunate is a medication used to treat malaria. The intravenous form is preferred to quinidine for severe malaria. Often it is used as part of combination therapy. It is not used for the prevention of malaria.
  • Artesunate can be given by injection into a vein, injection into a muscle, or taken by mouth.
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Chloroquine Phosphate

Chloroquine Phosphate
 
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Approx. Rs 1,250 / KilogramGet Latest Price

Product Details:
Molecular FormulaC18H26N3CL.H3O4P
Purity99%
AppearanceWhite powder
CAS NO50-63-5USD
Extraction TypeSolvent Extraction
Shelf Life2 years
Test MethodHPLC

Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication.

 

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Chlorphenesin

Chlorphenesin
 
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Approx. Rs 700 / KilogramGet Latest Price

Product Details:
UsageLaboratory
Packaging Size25 Kg
Packaging TypeDrums
ColorWhite
Solubility100%
Molecular Weight202.64
Molecular FormulaC9H11ClO3
Grade StandardReagent Grade
Physical StatePowder
BrandSalus
CAS Registry Number104-29-0
Synonyms(4-Chlorophenoxy)-1,2-propanediol

Chlorphenesin, a preservative, is widely used in cosmetics and compatible with most preservatives, including potassium sorbate, sodium benzoate, and methylisothiazolinone. In cosmetics and personal care products, Chlorphenesin helps to prevent or retard the growth of microorganisms, and thus protects the product from spoiling. Chlorphenesin may also function as a cosmetic biocide, which means that it helps prevent the growth of microorganisms on the skin which reduces or prevents odor.
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Lumefantrine

Lumefantrine
 
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Approx. Rs 1,900 / KilogramGet Latest Price

Product Details:
UsageIndustrial
Packaging Size25 Kg
Dosage FormPowder
Type Of APIAnti Malarial
Packaging Type25 Kg
BrandChemical Crunch
Purity99%
ColorWhite
AppearanceYellow Powder
CAS No82186-77-4
Molecular FormulaC30H32Cl3NO

lumefantrine is a fluorene derivative that is used in combination with artemether for the treatment of malaria (see artemether-lumefantrine combination).
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Methocarbamol

Methocarbamol
 
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Approx. Rs 1,200 / KilogramGet Latest Price

Product Details:
Usage/ApplicationAnti Malarial
Physical StatePowder
UsageLaboratory
Molecular FormulaC11H15NO5
Packaging Type25 Kg Drums
ColorWhite
Pack Size25 Kg
Type Of APIInnovative
BrandSalus
Molecular Weight241.24
CAS No532-03-6
SynonymsGuaiacol glyceryl ether carbamate; Glycerylguaiacolate carbamate

Methocarbamol is a central muscle relaxant used to treat skeletal muscle spasms. Under the trade name Robaxin, it is marketed by Actient Pharmaceuticals in the United States and Pfizer in Canada. The mechanism of action of methocarbamol is currently unknown, but may involve the inhibition of carbonic anhydrase.
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Quinine Hydrochloride

Quinine Hydrochloride
 
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Approx. Rs 7,500 / KilogramGet Latest Price

Product Details:
UsageLaboratory
Dosage FormPowder
Packaging Size25 Kg
Packaging TypeDrums
BrandChemical Crunch
Solubility100%
ColorWhite
Type Of APIAnti Malarial
AppearanceWhite crystalline powder
CAS No60-93-5
CertificateKOSHER,Halal,ISO9001;IQNET
EINECS No205-003-2
Purity99%

Quinine Hydrochloride is an alkaloid of cinchona that was once widely used to control and prevent malaria; it also has analgesic, antipyretic, mild oxytocic, cardiac depressant, and sclerosing properties, and it decreases the excitability of the motor end plate. It is used as the dihydrochloride, hydrochloride, or sulfate salt in the treatment of resistant falciparum malaria.
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Quinine Sulphate

Quinine Sulphate
 
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Approx. Rs 5,500 / KilogramGet Latest Price

Product Details:
AppearanceA white or almost white powder
Boiling Point911.6 Degree C at 760 mmHg
CAS No6119-70-6
EINECS No212-359-2
Flash Point505.1 Degree
Melting Point166 Degree C
Molecular Formula2(C20H24N2O2).H2SO4.2(H2O)
Molecular Weight746.912
Purity99%

Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to Plasmodium falciparum that is resistant to chloroquine when artesunate is not available. While used for restless legs syndrome, it is not recommended for this purpose due to the risk of side effects.
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