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Anti Diabetic

Our range of products include canagliflozin hemihydrate, diazoxide, empagliflozin, glibenclamide, glipizide and glyburide glibenclamide.
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Canagliflozin Hemihydrate

Canagliflozin Hemihydrate
 
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Approx. Rs 2.41 Lakh / KilogramGet Latest Price

Product Details:
Usage/ApplicationAnti Diabetic
Product TypeAnti Diabetic
Packaging Size25 Kg
Packaging TypeDrums
FormPowder
BrandChemical Crunch
Expiry Date2 Year
Manufactured ByChina
ColorWhite
Cas Number928672-86-0
Molecular FormulaC48H52F2O11S2
Molecular Weight907.05

If a person needs to take two anti-diabetic drugs, canagliflozin is recommended as a possible treatment for people with type 2 diabetes when taken with metformin hydrochloride, only if the person:

  • Cannot take a sulfonylurea or
  • Is at significant risk of hypoglycaemia or its consequences


If a person needs to take three anti-diabetic drugs, canagliflozin is recommended as a possible treatment when taken with either metformin hydrochloride and a sulfonylurea, or metformin hydrochloride and a thiazolidinedione.


Canagliflozin is also recommended as a possible treatment when taken with insulin, with or without other anti-diabetic drugs.

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Diazoxide

Diazoxide
 
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Approx. Rs 2.97 Lakh / KilogramGet Latest Price

Product Details:
BrandChemical Crunch
Usage/ApplicationAnti Diabetic
Packaging Size25 Kg Drums
Packaging TypeDrums
FormPowder
CAS Registry Number364-98-7
EINECS206-668-1
Molecular FormulaC8H7ClN2O2S
Molecular Weight230.67
Synonyms7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide

Diazoxide is a benzothiadiazine derivative which functions as a selective KIR6 (ATP-dependent K+) channel activator and calcium channel blocker. As a result membrane permeability increases the flow of K+ across the membrane, which turns off voltage gated calcium channels. This inhibition in action potential causes a relaxation in smooth muscle. Studies suggest that Diazoxide acts as a peripheral vasodilator. In addition, Diazoxide is used in diabetic studies to increase glucose concentrations in plasma, inhibit the secretion of insulin by β cells of the pancreas, increase the release of catecholamines, and hepatic output of glucose in vitro.

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Empagliflozin

Empagliflozin
 
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Approx. Rs 7 Lakh / KgGet Latest Price

Product Details:
AppearanceWhite powder
ApplicationPharma grade or research purpose
Assay99%
CAS No864070-44-0
Molecular FormulaC23H27ClO7
Molecular Weight450.91
StoragePreserve in tight,light-resistant containers in a cool place
Supply Ability50kg/month

Description:

  • Empagliflozin, also known as BI10773, is drug approved for the treatment of type 2 diabetes in adults in 2014. Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), and causes sugar in the blood to be absorbed by the kidneys and eliminated in urine. Empagliflozin is an inhibitor of the sodium glucose co-transporter-2 (SGLT-2), which is found almost exclusively in the proximal tubules of nephronic components in the kidneys. SGLT-2 accounts for about 90 percent of glucose reabsorption into the blood.
  • Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor used to treat type 2 diabetes to improve glycemic control in adults


Synonyms:

  • BI 10773; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[[(3S)-tetrahydro-3-furanyl]oxy]phenyl]methyl]phenyl]-D-glucitol
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Glibenclamide

Glibenclamide
 
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Approx. Rs 4,690 / KilogramGet Latest Price

Product Details:
Usage/ApplicationAnti Diabetic
Product TypeAnti Diabetic
BrandChemical Crunch
Grade StandardPharma Grade
Packaging Size25 Kg
Packaging Type25 Kg Drums
Age GroupAll
SolubilityShould conforms
Assay99.0%~101.0%
AppearanceWhite or almost white crystalline powder
FormulaC23H28ClN3O5S
Melting Point169 Degree C~174 Degree C

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Sulfonylureas bind to ATP-dependent K+channels in beta cells of the pancreas, depolarizing them and stimulating the release of Ca2+, which in turnstimulates insulin production. Glyburide (Glibenclamide) is an ATP-dependent K+ channel (KIR6, KATP) and CFTR Cl- channel blocker.Thiscompound inhibits recombinant CFTR Cl- channels

Specifications:

Identification

IR

Related Substance

Impurity A: ≤0.4%

Impurity B: ≤0.5%

Other impurity: ≤0.2%

Total impurities: ≤ 0.5%

Loss on Drying

≤1.0%

Heavy metals

≤20ppm

Sulphated ash

≤0.1%

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Glipizide

Glipizide
 
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Approx. Rs 19,320 / KilogramGet Latest Price

Product Details:
Packaging Size25 Kg
Usage/ApplicationAnti Diabetic
Packaging Type25 Kg Drums
BrandChemical Crunch
Age GroupAll
Product TypeAnti Diabetic
PurityGreater than 99%
UsageGlipizide is an antidiabetic drug.
AppearanceGlipizide Powder
CAS No29094-61-9
Shelf Life2 years

Glipizide is an oral rapid- and short-acting anti-diabetic drug from the sulfonylurea class. It is classified as a second generation sulfonylurea, which means that it undergoes enterohepatic circulation. Second-generation sulfonylureas are both more potent and have shorter half-lives than the first-generation sulfonylureas.

Specifications:

Category

Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.

Storage

Glipizide should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.

 

 

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Glyburide Glibenclamide

Glyburide Glibenclamide
 
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Approx. Rs 12,000 / KilogramGet Latest Price

Product Details:
CAS No10238-21-8
CategoryAPI
Intensity for Tolbutamide200 ~ 250 times
Molecular FormulaC23H28ClN3O5S
Molecular Weight494.0
Purity99.50%

Glyburide (Glibenclamide) is a sulfonylurea compound that modulates insulin production. Hypoglycemic drugs, for the treatment of mild, non insulin dependent diabetes. 2. Glibenclamide belongs to the second generation oral sulfonylurea drugs, with the mechanism of tolbutamide, its hypoglycemic effect is the strongest sulfonylurea. Be selective effect on pancreatic beta cells, promote the secretion of insulin, can enhance the hypoglycemic effect of exogenous insulin, insulin receptor after strengthening effect. 3. Glibenclamide is one of the drugs currently used to treat type 2 diabetes, the most often used, because the utility function is fast and strong, so after the application has obvious effect, can effectively control blood sugar, high blood sugar etc.

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Linagliptin

Linagliptin
 
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Approx. Rs 56,000 / KilogramGet Latest Price

Product Details:
AppearanceWhite powder
CAS Registry Number668270-12-0
ColourWhite
Molecular FormulaC25H28N8O2
Molecular Weight472.54
Packing25 Kg Drums

Linagliptin, also known as BI-1356, is a DPP-4 inhibitor developed for treatment of type II diabetes.

Synonyms:

8-[(3R)-3-Amino-1-piperidinyl]-7-(2-butynyl)-3,7-dihydro-3-methyl-1-[(4-methyl-2-quinazolinyl)methyl]-1H-purine-2,6-dione

 

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Metformin

Metformin
 
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Approx. Rs 350 / KilogramGet Latest Price

Product Details:
AppearanceWhite powder
Assay99%min Metformin HCL
CAS1115-70-4
CertificateISO 9001
Molecular FormulaC4H12ClN5
StorageCool Dry Place
TestHPLC

Description:

Metformin is the first-line medication for the treatment of type 2 diabetes.This is particularly true in people who are overweight. It is also used in the treatment of polycystic ovary syndrome.Limited evidence suggests metformin may prevent the cardiovascular disease and cancer complications of diabetes.It is not associated with weight gain. The main function of Hydrochloride is to reduce the secretion of glucagon from A cells, promote the conversion of glucose to glycogen. It also does not stimulate the secretion of insulin by beta cells.

 

HRK Provide Metformin HCL pure powder Metformin HCL price CAS 1115-70-4 Metformin HCL

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